Tuberculosis, a severe bacterial infection is caused by the Mycobacterium tuberculosis and continues to be one of the main causes of morbidity and mortality.A study on the immunological and structural characteristics of a protein belonging to the PPE family of Mycobacterium tuberculosis was done by insilico analysis and reveals that Rv2430c can be used as a possible diagnostic marker for active TB infection. Rv2430c showed statistically significant immune response pointing to the ability of this ORF to differentiate between TB and non TB patients.

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K.Rohini is a Lecturer in the Faculty of Medicine, AIMST University, Malaysia. Though teaching biochemistry is her passion she holds a Masters in Clinical Microbiology, Bachelors in Education and Post Graduate Diplomas in Forensic Science and Bioinformatics. She has published papers on Biochemistry, Bioinformatics & Nanotechnology.