The role of nutrition in neoplasia has been of longstanding concern. The subject was addressed by investigators in the first decade of this century, but was dropped. Vigorous attention was paid to this area of oncology in the 1940s, primarily due to the efforts of Dr. A. Tannenbaum at the Michael Reese Hospital in Chicago and the group at the University of Wisconsin in Madison. However, interest waned again until the 1970s when the question of diet and cancer was addressed and it has since been at the forefront of cancer research. The present volume (7) of Human Nutrition: A Comprehensive Treatise summarizes current knowledge in the area of nutrition and cancer. The first chapter is an overview written by John Higginson, whose contribution to understanding of cancer and nutrition spans several decades. The next essays cover epidemiology and physiology. The ensuing chapters address, in tum, those dietary factors relating to nutrition and cancer, namely, carbohydrates, protein, fat, cholesterol, calories, lipotropics, fiber, fruits and vegetables, vitamins, and alcohol. In a field moving as rapidly as this one is now, we can expect to miss a few late-breaking developments, but generally, the literature has been well covered through some time in 1988. Work relating to the effects of diet on oncogenes is in its very early development and has not been addressed as an entity per se.

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Inhaltsangabe1 Nutrition and Human Cancer.- 2 Epidemiologic Approaches to the Study of Diet and Cancer.- 3 A Comparison of the Changes in Carbohydrate, Fat, and Protein Metabolism Occurring with Malignant and Benign Tumors and the Impact of Nutritional Support.- 4 Carbohydrate and Cancer.- 5 Dietary Protein and Cancer.- 6 Fat and Cancer.- 7 Serum Cholesterol and Human Cancer.- 8 Lipotropic Factors and Carcinogenesis.- 9 The Effects of Caloric Restriction on Neoplasia and Age-Related Degenerative Processes.- 10 Dietary Fiber and Cancer.- 11 Chemoprevention by Nonnutrient Components of Vegetables and Fruits.- 12 Vitamins and Cancer.- 13 Interrelationships of Alcohol and Cancer.- Effects of Dietary Constituents on Carcinogenesis in Different Tumor Models: An Overview from 1975 to 1988.- 1. Preface.- 2. Introduction.- 3. Materials and Methods.- 4. Results.- 4.1. Colon.- 4.2. Urinary Bladder.- 4.3. Liver.- 4.4. Esophagus.- 4.5. Forestomach.- 4.6. Glandular Stomach.- 4.7. Skin.- 4.8. Respiratory Tract.- 4.9. Mammary Gland.- 4.10. Pancreas.- 5. Comments.- 6. References.