Inhaltsangabe1. Overview.- Biochemical Engineering - Past, Present and Future.- Strategic Planning and New Directions in Biochemical Engineering.- New Biocatalytic Functions of Microorganisms and Their Industrial Applications.- 2. Gene and Protein Engineering.- Development of a Bacillus brevis Host-Vector System for Efficient Heterologous Protein Production and Its Application to Protein Engineering.- Chimeric Receptor Made from IgM and EGFR that Induces Phosphorylation Upon Binding with Antigen.- Molecular Cloning of Feline Interferon cDNA by Direct Expression and Its Mass Production Using Silkworm.- Expression of Human Calcitonin in Escherichia coli.- Control of Gene Expression and Overproduction of Useful Heterologous Protein by Using an On-Line Sensor.- Expression and Secretion of Cloned Proteins in Recombinant Saccharomyces cerevisiae.- Plasmid Loss Probability in Escherichia coli as a Function of the Growth Rate of Plasmid-Bearing Cells. I: Variation During Continuous Cultures.- Plasmid Loss Probability in Escherichia coli as a Function of the Growth Rate of Plasmid-Bearing Cells. II: Modelling for Continuous Cultures.- Cloning and Expression of the Xylose (Glucose) Isomerase Gene from the Thermophile Thermus thermophilus HB8.- Mutagenesis Studies on the Amino Acid Residues Involved in an Iron-Binding Domain and a Catalytic Site of Human 5-Lipoxygenase.- Technology of Production of Recombinant Prourokinase.- High Level Expression and Secretion of Biologically Active Leech Hirudin Variant 1 (HV1) by Escherichia coli.- Transfer of Isolated Nuclei of Saccharomyces cerevisiae Into Anucleated Protoplasts of Nectaromyces species.- 3. Enzyme Engineering.- In Vitro Protein Refolding.- Nitrile Hydratase: Investigation of Its Light-Induced Activation.- Cloning of Bacillus licheniformis Amylase Gene and Its Application to Synthesis of Branched Oligosaccharides.- Aldolases for Use in Carbohydrate Synthesis: Enzymatic Reaction Engineering as a Tool for Process Optimization.- Bioconversion of Gaseous Substrate by Methylotrophic Hansenula polymorpha in a Gas-Solid Bioreactor.- Asymmetric Hydrolysis of Phenylglycidate Ester by Esterase from Serratia marcescens.- D-Threonine Aldolase and Its Application to D-ß-Hydroxy-a-Amino Acid Synthesis.- Improvement of Enzymatic Properties by Hydrophobic Interaction.- The Effect of Amphopathics on the Properties of Enzymes (Lipase, Cholinesterase, Cellulase).- Modified Cellulase with Amphiphilic Copolymers: Solubilization in Organic Solvent.- Aminoacylase-Catalyzed Synthesis of N-Acyl Amino Acid from Fatty Acid or Its Ethyl Ester and Amino Acid.- Peptide Synthesis in Organic Solvent with an Immobilized Enzyme.- A Novel Interesterification Process for Fats and Oils Using Acetone-Dried Fungus Immobilized in Biomass Support Particles.- Fractionation of Cellulase Components by Affinity Precipitation: Production of Cellobiose by Enzymatic Hydrolysis.- Separation of Positional Isomers by Combined Use of Enzymatic Hydrolysis and Extraction.- Studies on the Synthesis and Properties of the Mimics with Glutathione Peroxidase Activity and Preparation of the Conjugate of Mimic-Antibody.- Direct Synthesis of Cyclodextrin in a Heterogeneous Enzyme Reaction System Containing Insoluble Extruded Starch.- 4. Fermentation Technology.- Engineering and Genetic Approaches to Optimization of Recombinant Fermentation Process.- Computer-Controlled Fed-Batch Cultivation of a Recombinant Escherichia coli for Overproduction of Human Interleukin-2.- Production of Recombinant HTLV-I Envelope Protein.- Computer-Controlled High Cell Density Cultivation of Recombinant Escherichia coli Producing ß-Galactosidase.- Use of an Adaptive Control Strategy for the Production of Exotoxin A from High Density Culture of Recombinant Escherichia coli.- Effective Extracellular Production of Heterologous Proteins by Automated Fed-Batch Cultures of Recombinant Microorganisms Carrying Excretion Plasmid Vectors.- Production of Antifungal Peptide Produced by Baci

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