This textbook addresses the growing international need for a practical manual that teaches physicians how to apply cold atmospheric pressure plasma (CAP) in the day-to-day provision of patient healthcare. The book introduces readers to the concept of CAP, how it works, and how safe it is, before describing several diseases and other medical indications for its application. The book subsequently provides guidelines for daily clinical practice, e.g. for treating chronic wounds, decontaminating infected skin lesions, and rendering multi-resistant bacteria inert, as well as a detailed overview of plasma devices. In closing, it addresses organizational aspects, which are essential to cultivating and maintaining quality standards in the application of cold medical plasma. This textbook offers a unique educational resource and provides relevant information on plasma medicine as an emerging multidisciplinary discipline. Practitioners will appreciate this integrated, comprehensive guide, which is also suitable for advanced students of medicine and dentistry, and for nurses serving on plasma-assisted medical teams.

Hans-Robert Metelmann (M.D., D.M.D., Ph.D.) is senior professor of the Department of Oral and Maxillofacial Surgery/Plastic Surgery at Greifswald University Medicine, Greifswald, Germany. He trained at the Cancer Therapy and Research Center at the University of Texas at San Antonio, USA. He is head of the National German Center of Plasma Medicine and received the Plasma Medicine Award of the International Society for Plasma Medicine in 2018. Thomas von Woedtke (D.Sc., Ph.D.) is Professor for Plasma Medicine at Greifswald University Medicine and Program Manager Plasma Medicine at Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany and member of the board of INP. He is deputy head of the National German Center of Plasma Medicine. KlausDieter Weltmann (D.Sc., Ph.D.) is chairman of the board of Leibniz Institute for Plasma Science and Technology (INP) and Head of the Research Division Plasmas for Environment and Health. He held a professorship for Experimental Physics at Greifswald University and a visiting professorship for Applied Physics at New York University, NYU Tandon School of Engineering. He is member of the board of the National German Center of Plasma Medicine. Steffen Emmert (M.D., Ph.D.) is professor, Dean for Student Affairs and Director of the Clinic and Policlinic for Dermatology and Venerology at the University Medical Center, Rostock, Germany. He was trained at the National Institutes of Health in the USA, is involved in the plasma medicine treatment guideline project of the Association of Scientific Medical Societies in Germany and member of the board of the National German Center of Plasma Medicine.